Side Effects Contraindications
▶ Myopathy
▶ Flushing
▶ Hyperglycemia & hyperuricemia
▶ Hepatotoxicity
▶ Active liver disease
▶ Arterial bleeding
▶ Pregnant or nursing women or those
desiring to become pregnant
▶ Myopathy
▶ Flushing
▶ Hyperglycemia & hyperuricemia
▶ Liver enzyme elevations
▶ Active liver disease
▶ Arterial bleeding
▶ Pregnant or nursing women or those
desiring to become pregnant
▶ Myopathy
▶ Liver enzyme elevations
▶ Active liver disease
▶ Pregnant or nursing women or those
desiring to become pregnant
▶ 80-mg dose of simvastatin is only for
previous users
▶ Myopathy
▶ Liver enzyme levations
▶ Active liver disease
▶ Pregnant or nursing women or those
desiring to become pregnant
17
Side Effects Warnings Comments
• Increased hepatic fat
(hepatic steatosis)
• Injection site reactions
• Flu-like symptoms
• Nausea
• Headache
• serum transaminases
Risk of hepatotoxicity Available only through
a restricted program
• Increased hepatic fat
(hepatic steatosis)
• Diarrhea
• Nausea
• Vomiting
• Dyspepsia
• Abdominal pain
• serum transaminases