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32 Hypertension in Patients With Comorbidities Stable Ischemic Heart Disease COR LOE Recommendations I SBP: B-R In adults with SIHD and hypertension, a BP target of less than 130/80 mm Hg is recommended. DBP: C-EO I SBP: B-R Adults with SIHD and hypertension (BP ≥130/80 mm Hg ) should be treated with medications (e.g., guideline-directed management and therapy (GDMT) beta blockers, ACE inhibitors, or ARBs) for compelling indications (e.g., previous MI, stable angina) as first-line therapy, with the addition of other drugs (e.g., dihydropyridine CCBs, thiazide diuretics, and/or mineralocorticoid receptor antagonists) as needed to further control hypertension. DBP: C-EO I B-NR In adults with SIHD with angina and persistent uncontrolled hypertension, the addition of dihydropyridine CCBs to GDMT beta blockers is recommended. IIa B-NR In adults who have had a MI or acute coronary syndrome, it is reasonable to continue GDMT beta blockers beyond 3 years as long-term therapy for hypertension. IIb C-EO Beta blockers and/or CCBs might be considered to control hypertension in patients with coronary artery disease (without HFrEF) who had an MI more than 3 years ago and have angina.

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