7
www.SCAI.org/Guidelines
Figure 7. Diastolic Dysfunction in Patients with HFpEF
e EDPVR is shied up and to the le in these patients with HFpEF. e poor diastolic
compliance of the le ventricle is also reflected by the stiffness constant derived from the same
data. Reprinted with permission from Zile M et al. N Engl J Med 2004;350:1953–1959.
Figure 6. Relationship Between Resistance and Compliance
in the Pulmonary Circulation
In the pulmonary circulation, resistance and compliance are inversely related, as illustrated
from this plot of patient hemodynamics taken from multiple catheterization laboratories.
e product of resistance (R) and compliance (C) is remarkably constant over age or
interstitial lung disease. However, the RC relationship moves to the le with increasing
PCWP, suggesting increased pulsatile relative to resistive aerload to the RV when there
is pulmonary congestion. e arrow represents a theoretical heart failure patient with
PH out of proportion to the PCWP. Reprinted with permission from Tedford RJ et al.
Circulation. 2012:125(2):289-297.
