6
Figure 5. Relationship of Flow and PAP in Normal Patients
and those with PH
In normal patients and those with scleroderma without PH (Scleroderma NoPH), the
mean PA pressure only modestly rises despite a significant increase in flow. In contrast,
patients with PAH or with scleroderma and borderline PH (Scleroderma BlnPH) cannot
accommodate an increase in flow without a concomitant increase in the mean PA pressure.
A mPAP-CO slope of >3.0 can indicate the presence of pulmonary vascular disease.
Reprinted with permission Lewis G, et al. Circulation 2013;128:1470-1479.
