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Dry Eye Syndrome

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10 Management Î Contributing ocular factors such as blepharitis or meibomianitis should also be treated. (II++, G, D) Î Azithromycin should be used with caution to treat dry eye in patients who have cardiovascular problems. (II+, G, S) Î Eyelid abnormalities resulting from blepharitis should be corrected. (II++, M, D) Î Eyelid abnormalities resulting from trichiasis should be corrected. (III, In, D) Î Eyelid abnormalities resulting from lid malposition should be corrected. (III, In, D) Î Low-dose topical corticosteroid therapy can be used at infrequent intervals for short periods of time (i.e., several weeks) to suppress ocular inflammation. (I-, M, D) Î Patients prescribed corticosteroids for dry eye should be monitored for adverse effects such as increased intraocular pressure and cataract formation. (III, G, S) Î Omega-3 fatty acid products without ethyl esters may be beneficial in the treatment of dry eye, though the evidence is insufficient to establish the effectiveness of any particular formulation. (I-, In, D) Î Use of systemic omega-3 fatty acid supplements for dry eye treatment has been reported to be potentially beneficial, but there is no evidence of their efficacy. (I-, In, D) Î For patients with aqueous tear deficiency, punctal occlusion is considered when the medical means of aqueous enhancement are ineffective or impractical. (I++, G, S) Î Punctal plugs may be helpful in moderate to severe cases of aqueous deficient dry eye and meibomian gland dysfunction. (I++, G, S) Î Patients treated with punctal plugs should be monitored regularly to ensure that the plugs are present and in the proper position. (III, In, D) Î The largest plug that can be inserted should be used to reduce the likelihood of extrusion. (III, In, D) Î Patients who benefit from having punctal plugs in place but spontaneously lose them may have the lost plug(s) replaced or undergo permanent closure of their punctum by a thermal cautery or alternative means. (III, In, D) Î Noninvasive therapies such as eyeglass side shields and moisture chambers can be used. (III, G, S)

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