8
Treatment
Table 4. Targets for Invasive Septal Reduction Therapies
Outcomes
Rate (%)
Myectomy
Alcohol Septal
Ablation
30-d mortality ≤1 ≤1
30-d adverse complications (tamponade, LAD
dissection, infection, major bleeding )
≤5 ≤5
30-d complete heart block resulting in need for
permanent pacemaker
≤5 ≤10
Mitral valve replacement within 1 y ≤5
More than moderate residual mitral regurgitation ≤5 ≤5
Repeat procedure rate ≤3 ≤10
Symptomatic improvement
(eg, ≥1 NYHA functional class)
>90 >90
Rest and provoked LVOT gradient <50 mm Hg >90 >90
LAD indicates le anterior descending ; LVOT, le ventricular outflow tract; and NYHA,
New York Heart Association.
6.1. Clinical Diagnosis
COR LOE
Recommendation
1 B-NR
1. In patients with suspected HCM, comprehensive physical
examination and complete medical and 3-generation family
history is recommended as part of the initial diagnostic
assessment (Table 5, Table 6).
6. Diagnosis, Initial Evaluation, and Follow-Up
