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Other Comorbidities
COR LOE
Recommendations
Hypertension Aer Renal Transplantation
IIa SBP:
B-NR
Aer kidney transplantation, it is reasonable to treat patients with
hypertension to a BP goal of less than 130/80 mm Hg.
DBP:
C-EO
IIa B-R Aer kidney transplantation, it is reasonable to treat patients with
hypertension with a calcium antagonist on the basis of improved
GFR and kidney survival.
Peripheral Artery Disease
I B-NR Adults with hypertension and PAD should be treated similarly to
patients with hypertension without PAD.
Diabetes Mellitus
I SBP:
B-R
SR
In adults with DM and hypertension, antihypertensive drug
treatment should be initiated at a BP of 130/80 mm Hg or higher
with a treatment goal of less than 130/80 mm Hg.
DBP:
C-EO
I A
SR
In adults with DM and hypertension, all first-line classes of
antihypertensive agents (i.e., diuretics, ACE inhibitors, ARBs,
and CCBs) are useful and effective.
IIb B-NR In adults with DM and hypertension, ACE inhibitors or ARBs
may be considered in the presence of albuminuria.
Atrial Fibrillation
IIa B-R Treatment of hypertension with an ARB can be useful for
prevention of recurrence of atrial fibrillation (AF).
Valvular Heart Disease
I B-NR In adults with asymptomatic aortic stenosis, hypertension should
be treated with pharmacotherapy, starting at a low dose and
gradually titrating upward as needed.
IIa C-LD In patients with chronic aortic insufficiency, treatment of systolic
hypertension with agents that do not slow the heart rate (i.e.,
avoid beta blockers) is reasonable.
Aortic Disease
I C-EO Beta blockers are recommended as the preferred antihypertensive
agents in patients with hypertension and thoracic aortic disease.