30
Treatment
Beta blockers—
cardioselective and
vasodilatory
Nebivolol 5–40 1
Beta blockers—
noncardioselective
Nadolol 40–120 1
Propranolol IR 80–160 2
Propranolol LA 80–160 1
Beta blockers—
intrinsic
sympathomimetic
activity
Acebutolol 200–800 2
Penbutolol 10–40 1
Pindolol 10–60 2
Beta blockers—
combined alpha- and
beta-receptor
Carvedilol 12.5–50 2
Carvedilol phosphate 20–80 1
Labetalol 200–800 2
Direct renin
inhibitor
Aliskiren 150–300 1
Alpha-1 blockers Doxazosin 1–16 1
Prazosin 2–20 2 or 3
Terazosin 1–20 1 or 2
Central alpha
2
-
agonist and other
centrally acting drugs
Clonidine oral 0.1–0.8 2
Clonidine patch 0.1–0.3 1 weekly
Methyldopa 250–1000 2
Guanfacine 0.5–2 1
Direct vasodilators Hydralazine 100–200 2 or 3
Minoxidil 5–100 1–3
a
Dosages may vary from those listed in the FDA approved labeling (available at
https://dailymed.nlm.nih.gov/dailymed/).
Table 14. Oral Antihypertensive Drugs (cont'd)
Class Drug
Usual Dose,
Range (mg/d)
a
Daily
Frequency
