7
Neoplasia
• Basal cell carcinoma, squamous cell carcinoma (Marjolin ulcer), malignant
melanoma, angiosarcoma, cutaneous lymphoma, papillomatosis cutis carcinoides,
keratoacanthoma
Infection
• Bacterial: furuncles, ecthyma, mycobacterioses, syphilis, erysipelas, anthrax,
diphtheria, chronic vegetative pyodermia, tropical ulcer
• Viral: herpes, variola virus, cytomegaly
• Fungal: sporotrichosis, histoplasmosis, blastomycosis, coccidioidomycosis
• Protozoal: leishmaniasis
Medication
• Hydroxyurea, leflunomide, methotrexate, halogens, coumarin, vaccinations,
ergotamine, infiltration cytostatic agents
Genetic defect
• Klinefelter syndrome, Felty syndrome, TAP1 mutation, leukocyte adhesion
deficiency, inherited hypercoagulable factors
Skin disorder
• Pyoderma gangrenosum, necrobiosis lipoidica, sarcoidosis, perforating dermatosis,
Langerhans cell histiocytosis, papulosis maligna atrophicans, bullous skin diseases
Modified from Dissemond J, Korber A, Grabbe S. Differential diagnosis of leg ulcers.
J Dtsch Dermatol Ges. 2006;4:627-634.
Table 3. Diagnosis of Peripheral Arterial Disease (PAD)
(cont'd)
