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Treatment of Patients with Schizophrenia

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21 Typical dose (mg) Maximum dose (mg) Dosing frequency Need for initial oral supplementation 6.25–25 every 2–4 weeks 100 2–4 weeks Decrease oral dose by half after first injection, then discontinue with second injection 50–200 (10–15 times previous oral dose) 450/month 4 weeks Taper and discontinue after two to three injections 400 400/month Monthly Continue oral for 14 days after initial injection 675 675 Single dose to initiate Aristada treatment or reinitiate treatment after a missed Aristada dose. Not for repeated dosing. Must be administered in conjunction with one 30 mg dose of oral aripiprazole. Monthly: 441, 662, 882 Every 6 weeks: 882 Every 2 months: 1,064 882/month Monthly: 441, 662, 882 Every 6 weeks: 882 Every 2 months: 1,064 There are two ways to initiate treatment: 1. Give one IM injection of Aristada Initio 675 mg and one dose of oral aripiprazole 30 mg, or 2. Give 21 days of oral aripiprazole in conjunction with the first Aristada injection

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