22
Treatment
Long-acting injectable antipsychotic medications: dosing*
(cont'd)
Olanzapine Zyprexa
Relprevv
10 mg/day orally,
210 mg every 2
weeks for four
doses, or 405 mg
every 4 weeks
15 mg/day orally, 300
mg every 2 weeks
for four doses
20 mg/day orally, 300
mg every 2 weeks
Determined by oral
dose
Paliperidone
palmitate
Invega
Sustenna
3 mg oral
paliperidone,
give 39–78 mg IM
6 mg oral,
give 117 mg IM
9 mg oral,
give 156 mg IM
12 mg oral,
give 234 mg IM
234 mg IM on day 1
and 156 mg IM
1 week later, both
administered in the
deltoid muscle
Paliperidone
palmitate
Invega Trinza Conversion from
monthly Invega
Sustenna to every
3-month injections of
Invega Trinza:
78 mg, give 273 mg
117 mg, give 410 mg
156 mg, give 546 mg
234 mg, give 819 mg
Dependent on last
dose of monthly
paliperidone
Risperidone Risperdal
Consta
Oral risperidone to
Risperidone Consta IM:
≤3 mg/day, give
25 mg/2 weeks
>3 to ≤5 mg/day, give
37.5 mg/2 weeks
>5 mg/day, give
50 mg/2 weeks
25 every 2 weeks
Risperidone Perseris Oral risperidone
to subcutaneous
risperidone
extended release:
3 mg/day, give
90 mg/monthly
4 mg/day, give
120 mg/monthly
Determined by oral
dose
* This table includes information compiled from multiple sources. Detailed information on such
issues as dose regimen, dose adjustments, medication administration procedures, handling
precautions, and storage can be found in product labeling. It is recommended that readers
consult product labeling information for authoritative information on these medications.