10
Diagnosis
Table 3. Key Infectious and Noninfectious Differential
Diagnoses for Granulomatous Lesions within
Commonly Biopsied Sites
Leishmaniasis
Ｘ Ｘ
Echinococcosis
Ｘ Ｘ
Enterobius
Ｘ Ｘ
Dirofilaria
Ｘ
Noninfectious etiologies
Malignancy
Lymphoma
a
Ｘ Ｘ Ｘ Ｘ Ｘ
Sarcoid-like reaction to
tumor
a
Ｘ Ｘ Ｘ Ｘ Ｘ
Lymphomatoid
granulomatosis
Ｘ
Germ cell tumor
Ｘ
Autoimmune or immune dysfunction
ANCA-associated vasculitides
(GPA, MPA, and EGPA)
Ｘ Ｘ
GLIL associated with CVID
Ｘ Ｘ
Rheumatoid nodules
Ｘ
Langerhans cell histiocytosis
Ｘ Ｘ Ｘ Ｘ Ｘ
IgG4-related disease
Ｘ Ｘ Ｘ Ｘ Ｘ
Inflammatory bowel disease
Ｘ Ｘ Ｘ
Primary biliary cholangitis
Ｘ
Primary sclerosing cholangitis
Ｘ
Autoimmune hepatitis
