Hemochromatosis

AASLD Hemochromatosis

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Treatment Table 6. Response to Phlebotomy Treatment in Patients with HH Reduction of tissue iron stores to normal Improved survival if diagnosis and treatment before development of cirrhosis and diabetes Improved sense of well-being, energy level Improved cardiac function Improved control of diabetes Reduction in abdominal pain Reduction in skin pigmentation Normalization of elevated liver enzymes Reversal of hepatic fibrosis (in approximately 30% of cases) No reversal of established cirrhosis Elimination of risk of HH-related HCC if iron removal is achieved before development of cirrhosis Reduction in portal hypertension in patients with cirrhosis No (or minimal) improvement in arthropathy No reversal of testicular atrophy

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