Diagnosis
Table 4. Laboratory Findings in Patients with HH
Patients with HH
Normal
Subjects
Asymptomatic
Serum iron level (mcg/dL)
60-80
150-280
180-300
Transferrin saturation (%)
20-50
45-100
80-100
Men
20-200
150-1000
500-6000
Women
15-150
120-1000
500-6000
8000-30,000
Measurements
Symptomatic
Blood
Serum ferritin level (mcg/L)
Liver
Hepatic iron concentration
mcg/g dry weight
300-1500
2000-10,000
mcmol/g dry weight
5-27
36-179
Hepatic iron index
<1.0
> 1.9
> 1.9
0-1+
2+ to 4+
3+, 4+
a
140-550
Liver histology
Perls' Prussian blue stain
a
Hepatic iron index is calculated by dividing the hepatic iron concentration (in mcmol/g dry weight) by
the age of the patient (in years). With increased knowledge of genetic testing results in patients with
iron overload, the utility of the hepatic iron index has diminished.
