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AGACCS1772d
Disclaimer
is Guideline attempts to define principles of practice that should produce high-quality patient care.
It is applicable to specialists, primary care, and providers at all levels. is Guideline should not be
considered exclusive of other methods of care reasonably directed at obtaining the same results. e
ultimate judgment concerning the propriety of any course of conduct must be made by the clinician
aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the
authors endorse any product or service associated with the distributor of this clinical reference tool.
Abbreviations
AGA, American Gastroenterological Association Institute; CRC, colorectal cancer; FIT, fecal
immunochemical test; USMSTF, U.S. Multi-Society Task Force on Colorectal Cancer
Visit gastro.org/guidelinesapp to learn about the AGA Clinical Guidelines App.
Available for download on the iTunes and Google Play Store.
Table 5. USMSTF Recommendations for Persons With High-Risk
Family Histories Not Associated With Polyp Syndromes
Family history Recommended screening
Lynch Syndrome See Giardiello FM, Allen JI, Axilbund JE, et al.
Gastrointest Endosc. 2014;80:197–220.
Family Colon Cancer Syndrome X Colonoscopy every 3–5 years beginning 10
years before the age at diagnosis of the youngest
affected relative.
Colorectal cancer or an advanced
precancerous lesion (advanced adenoma or
sessile serrated polyp that is ≥10 mm in size
or has cytological dysplasia) diagnosed in a
single first degree relative at age <60 years
or in two first degree relatives at any age
Colonoscopy every 5 years beginning 10 years
before the age at diagnosis of the youngest
affected individual or age 40, whichever is earlier.
Colorectal cancer or an advanced
precancerous lesion in a single first-degree
relative diagnosed at age ≥60 years
Begin screening at age 40 years – tests and
intervals are as per the average-risk screening
recommendations. (Table 4)
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pocket guide digitally, visit GuidelineCentral.com/CRCScreening
