15
Table 6. Estimated Costs for Antiemetic Products
a
Agent Dose Schedule
Price Per
Dose (USD)
Total
Cost Per
Treatment
Cycle
(USD)
5-HT
3
receptor antagonist
Ondansetron IV 8 mg /
0.15 mg/kg
Prechemotherapy,
one dose
1.10 1.10
Ondansetron oral
(generic)
8 mg Twice daily on
days 1–3
6.50 6.50
Ondansetron oral
(brand)
8 mg Twice daily on
days 1–3
45.55 268.28
Ondansetron oral
dissolving tablet
(generic)
8 mg Every 12 hours as
needed, days 1–3
6.50 6.50
Ondansetron oral
dissolving tablet
(brand)
8 mg Every 12 hours as
needed, days 1–3
85.05 253.14
Ondansetron
oral soluble film
(brand)
8 mg Every 12 hours as
needed, days 1–3
75.82 225.46
Granisetron IV 1 mg or
0.01 mg/kg
IV
Prechemotherapy,
one dose
3.13 3.13
Granisetron oral 1 mg Once (2 mg ) on
day 1, 1 mg twice
daily on days 2, 3
6.50 14.36
Granisetron
transdermal
3.1 mg Prechemotherapy,
up to 7 days
467.00 467.00
Granisetron
extended-release
injection, for
subcutaneous use
b
10 mg Prechemotherapy,
and not more
frequently than
once every 7 days
b b
Dolasetron oral 100 mg Once daily on
days 1–3
100.83 330.50
Palonosetron IV 0.25 mg Prechemotherapy,
one dose
228.80 228.80
