ASCO GUIDELINES Bundle

Antiemetics (CINV)

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16 NK 1 receptor antagonists Aprepitant oral 125 mg Prechemotherapy, one dose 284.01 284.01 Aprepitant oral 80 mg Once daily on days 2, 3 182.14 364.28 Fosaprepitant IV 150 mg Prechemotherapy, one dose 299.87 299.87 Rolapitant 180 mg Prechemotherapy, one dose 610.50 610.50 Combination products Netupitant/ palonsetron) 300 mg/ 0.5 mg Prechemotherapy, one dose 632.35 632.35 Antipsychotics Olanzapine (generic) 5 mg Once daily on days 1–3 6.50 6.50 Olanzapine (generic) 10 mg Once daily on days 1–3 6.50 6.50 Olanzapine (brand) 5 mg Once daily on days 1–3 15.07 43.22 Olanzapine (brand) 10 mg Once daily on days 1–3 22.21 64.62 Dopaminergic antagonists Metoclopramide IV 1–2 mg/kg Prechemotherapy, one dose 99.50 99.50 Metoclopramide oral (generic) 0.5 mg/kg Every 6 hours, days 2–4 6.50 6.50 Metoclopramide oral (brand) 0.5 mg/kg Every 6 hours, days 2–4 65.00 192.99 Prochlorperazine IV 5–10 mg Prechemotherapy, every 6–8 hours, maximum 40 mg 11.93 11.93 Prochlorperazine oral 10 mg Every 6–8 hours as needed 6.50 6.50 Cannabinoids Nabilone oral 1–2 mg Twice daily, days 1–3 75.38 249.63 Dronabinol oral (generic) 5 mg/m 2 Every 2–4 hours as needed 184.70 223.94 c Dronabinol oral (brand) 5 mg/m 2 Every 2–4 hours as needed 314.60 941.80 c Treatment Table 6. Estimated Costs for Antiemetic Products a (cont'd)

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