Disclaimer
is Guideline attempts to define principles of practice that should produce high-quality patient
care. It is applicable to specialists, primary care, and providers at all levels. is Guideline
should not be considered exclusive of other methods of care reasonably directed at obtaining the
same results. e ultimate judgment concerning the propriety of any course of conduct must be
made by the clinician aer consideration of each individual patient situation.
Neither IGC, the medical associations, nor the authors endorse any product or service associated
with the distributor of this clinical reference tool.
Abbreviations
CXR, chest radiograph; HIV, human immunodeficiency virus; HPLC, high-performance
liquid chromatography; IGRA, interferon-γ release assay; LTBI, latent tuberculosis
infection; Mtb, Mycobacterium tuberculosis; RR, relative risk; TB, tuberculosis; TST,
tuberculin skin test
e guidelines provide evidence-based recommendations that have been developed
using GR ADE (Grading of Recommendations, Assessment, Development, and
Evaluation) methodolog y. GR ADE involves structured literature review, systematic
reviews and meta-analyses of combined data, and expert discussion to assess the
certainty in the evidence and determine the strength of each recommendation.
Source
Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J,
Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger
M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL. Official American oracic
Society/Infectious Diseases Society of America/Centers for Disease Control and
Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and
Children. Clin Infect Dis. 2017; 64(2):e1-e33.
e guidelines were a cooperative effort among the American oracic Society, Centers for
Disease Control and Prevention, and Infectious Diseases Society of America
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