3
Diagnosis
Critical limb ischemia
(CLI)
A condition characterized by chronic (≥2 wk) ischemic rest
pain, non-healing wound/ulcers, or gangrene in 1 or both legs
attributable to objectively proven arterial occlusive disease.
• The diagnosis of CLI is a constellation of both symptoms
and signs. Arterial disease can be proved objectively with
ankle-brachial index (ABI), toe-brachial index (TBI),
transcutaneous oxygen pressure (TcPO
2
), or skin perfusion
pressure. Supplementary parameters, such as absolute ankle
and toe pressures and pulse volume recordings, may also
be used to assess for significant arterial occlusive disease.
However, a very low ABI or TBI does not necessarily mean
the patient has CLI. The term CLI implies chronicity and is
to be distinguished from ALI.
In-line blood flow Direct arterial flow to the foot, excluding collaterals.
Functional status Patient's ability to perform normal daily activities required
to meet basic needs, fulfill usual roles, and maintain health
and well-being. Walking ability is a component of functional
status.
Nonviable limb Condition of extremity (or portion of extremity) in which loss
of motor function, neurological function, and tissue integrity
cannot be restored with treatment.
Salvageable limb Condition of extremity with potential to secure viability and
preserve motor function to the weight-bearing portion of the
foot if treated.
Structured exercise
program
Planned program that provides individualized recommendations
for type, frequency, intensity, and duration of exercise.
• Program provides recommendations for exercise progression
to assure that the body is consistently challenged to increase
exercise intensity and levels as functional status improves over
time.
• There are 2 types of structured exercise program for patients
with PAD:
1. Supervised exercise program
2. Structured community- or home-based exercise program
Table 1. Definition of PAD Key Terms (cont'd)
Term Definition
