4
Internet resources for PIDDs
URL Name/Description
http://www.aaaai.org American Academy of Allerg y, Asthma &
Immunolog y
http://www.esid.org European Society for Immunodeficiencies
http://www.
immunodeficiencysearch.com
Searchable database, clinical algorithms,
laboratory resources
http://www.info4pi.org Jeffrey Modell Foundation/Primary
Immunodeficiency Resource Center
http://www.ipidnet.org Immune Phenotyping in Primary
Immunodeficiency
http://www.ipopi.org International Patient Organization for Primary
Immunodeficiencies
http://www.primaryimmune.org Immune Deficiency Foundation
http://web16.kazusa.or.jp/rapid/ Resource of Asian Primary Immunodeficiency
Diseases (RAPID)
http://www.usidnet.org US Immunodeficiency Network (USIDNET)
Grading System for Recommendations
Category of Evidence Strength of Recommendation
Ia
Evidence from meta-analysis of
randomized controlled trials
A
Directly based on category I
evidence
Ib
Evidence from at least one randomized
controlled trial
B
Directly based on category
II evidence or extrapolated
recommendation from
category I evidence
IIa
Evidence from at least one controlled
study without randomization
C
Directly based on category
III evidence or extrapolated
recommendation from
category I or II evidence
IIb
Evidence from at least one other type of
quasiexperimental study
D
Directly based on category
IV evidence or extrapolated
recommendation from
category I, II, or III evidence
III
Evidence from nonexperimental
descriptive studies, such as comparative
studies, correlation studies, and case-
control studies
E
Directly based on category
LB evidence
IV
Evidence from expert committee reports
or opinions or clinical experience of
respected authorities, or both
F
Based on consensus of the
Joint Task Force on Practice
Parameters
LB
Evidence from laboratory-based
studies under IV Category of
Evidence
