9
Table 2. Guidelines for Diagnostic Work-up of Patients with
CU (cont'd)
Laboratory Evaluation (cont'd)
▶ Hepatitis B and C serologies
▶ Chest radiography, other imaging studies, or both
▶ Anti-nuclear antibody
▶ Rheumatoid factor, anti-citrullinated protein
▶ Cryoglobulin levels
▶ Serologic and/or skin testing for immediate hypersensitivity
▶ Thyroid autoantibodies
▶ Serum protein electrophoresis
More detailed laboratory tests, skin biopsies, or both merit consideration if urticaria is
not responding to therapy as anticipated.
Additional laboratory testing might be required before initiation of certain medications,
such as G6PD screening, before prescribing dapsone.
