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Table 9. Laboratory Monitoring of Alternative Agents for
Patients with Refractory CU
Alternative agent Baseline laboratory tests Monitoring on therapy
Montelukast None None
Hydroxychloroquine G6PD, LFT, BUN/Cr None
Dapsone G6PD, CBC, LFT Monthly: CBC, LFT × 6 mo
and then periodically
Sulfasalazine CBC, LFT, BUN/Cr Monthly: CBC, LFT, BUN/Cr
× 3 mo and then every 3 mo
Methotrexate CBC, LFT, BUN/Cr,
Chest x-ray
Every 2–4 wk: CBC, LFT,
BUN/Cr
Colchicine LFT, BUN/Cr None
Cyclosporine (CSA) CBC, LFT, BUN/Cr, K,
lipids
Every 2–4 wk: BUN/Cr, K, CSA
Periodic: lipids, glucose
Tacrolimus CBC, LFT, BUN/Cr, K,
lipids
Same as cyclosporine, except
check tacrolimus levels
Mycophenolate CBC, LFT, BUN/Cr First month: weekly CBC
en CBC every 2 wk for 2–3
mo and then monthly
Omalizumab None None
Immune globulin BUN/Cr, CBC Periodic monitoring of BUN/
Cr, CBC