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Drug-Susceptible Tuberculosis

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9 Daily Once-Weekly Twice-Weekly Thrice-Weekly 5 mg/kg (typically 300 mg ) 15 mg/kg (typically 900 mg ) 10–15 mg/kg - - - 20–30 mg/kg - - - b 10 mg/kg (typically 600 mg ) - - - 10 mg/kg (typically 600 mg ) 10–20 mg/kg - - - 10–20 mg/kg - - - b 5 mg/kg (typically 300 mg ) - - - Not recommended Appropriate dosing for children is unknown. Estimated at 5 mg/kg. 10–20 mg/kg e - - - - - - • Active tuberculosis: for children ≥12 y of age, same dosing as for adults, administered once weekly. • Rifapentine is not FDA-approved for treatment of active tuberculosis in children <12 y of age. See Table 9 - - - See Table 9 35 (30–40) mg/kg - - - 50 mg/kg - - - b See Table 10 - - - See Table 10 20 (15–25) mg/kg - - - 50 mg/kg - - - b 10–15 mg/kg total (usually 250–500 mg once or twice daily) ere are inadequate data to support intermittent administration. 15–20 mg/kg total (divided 1–2 times daily) 15–20 mg/kg total (usually 250–500 mg once or twice daily) 15–20 mg/kg total (divided 1–2 times daily)

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