8
Treatment
Table 2. Doses
a
of Antituberculosis Drugs for Adults
and Children
b
Drug Preparation Population
First-line drugs
Isoniazid Tablets (50 mg, 100 mg, 300 mg ); elixir (50 mg/5 mL);
aqueous solution (100 mg/mL) for intravenous or
intramuscular injection.
Note: Pyridoxine (vitamin B6), 25–50 mg/ day, is
given with INH to all persons at risk of neuropathy (eg,
pregnant women; breastfeeding infants; persons with
HIV; patients with diabetes, alcoholism, malnutrition, or
chronic renal failure; or patients with advanced age). For
patients with peripheral neuropathy, experts recommend
increasing pyridoxine dose to 100 mg/d.
Adults
Children
Rifampin Capsule (150 mg, 300 mg )
Powder may be suspended for oral administration.
Aqueous solution for intravenous injection.
Adults
c
Children
Rifabutin Capsule (150 mg )
Adults
d
Children
Rifapentine Tablet (150 mg film coated) Adults
Children
Pyrazinamide Tablet (500 mg scored) Adults
Children
Ethambutol Tablet (100 mg, 400 mg ) Adults
Children
f
Second-line drugs
Cycloserine Capsule (250 mg )
Adults
g
Children
Ethionamide Tablet (250 mg )
Adults
h
Children
