Selecting a Treatment Regimen
Figure 5. Necrotizing Group A Streptococcal Infections Early Aggressive Debridement and Drainage (1C) AND
Early Aggressive Antibiotic Rx (1C) Severe
piperacillin, or piperacillin/ tazobactam)
linezolid, erythromycin) + CWAA (Pen G,
PSIA (clinda mycin, Figure 6. Clostridial Infections
Early Aggressive Debridement and Drainage (1C) AND
Early Aggressive Antibiotic Rx (1C)
Parenteral penicillin 24 MU/d + PSIA (1C) Alternates
CWAA + PSIA Figure 7. Vibrio Infections
Early Aggressive Debridement and Drainage (1C) AND
Early Aggressive Antibiotic Rx (1C)
Cefotaxime + tetracycline or minocycline (1C) Alternates
Other CWAA or DNAIA + tetracycline or minocycline (1C) Moderate – Severe
Parenteral penicillin 24 MU/d ± PSIA (1C)
Strep TSS Consider IVIg (2C)
