Treatment
Figure 2. Antithrombotic Management of Heart Valve Disease Rheumatic Mitral Valve Disease
NSR Atrial diameter < 55 mm > 55 mm No treatment
Left atrial thrombus
VKA – target INR 2.5 (range 2.0-3.0)
Atrial fibrillation and/or previous systemic embolism
PMBV with Left Atrial Thrombus
VKA – target INR 3.0 (range 2.5-3.5) until thrombus resolution
Nonbacterial Thrombotic Endocarditis and Systemic or Pulmonary Emboli
Full dose IV UFH or subcutaneous LMWH
Patent Foramen Ovale or Atrial Septal Aneurysm Asymptomatic No treatment
VKA – target INR 2.5 (range 2.0-3.0)
Consider device closure
Recurrent DVT despite aspirin
AND cryptogenic stroke With DVT
Aspirin 50-100 mg/d
