Figure 1. Prosthetic Valves Mechanical Mitral Aortic Bioprosthetic NSR Mitral
or prophy dose UFH
Full or prophy dose LMWH
Bridging (range 2.0-3.0)
VKA – target INR 2.5
VKA – target INR 3.0 (range 2.5-3.5)
Consider adding antiplatelet Rx
Endocarditis Infective
Suspend VKA pending invasive procedures
Fibrinolysis Surgery Right PVT Left × 3 mo × 3 mo
Aspirin 50-100 mg/d + clopidogrel (75 mg/d)
After 3 mo
Aspirin 50-100 mg/d
Antiplatelet Rx
Aortic Transcatheter NSR Valve Repair Aortic
Mitral NSR
Thrombus < 0.8 cm2
Thrombus ≥ 0.8 cm2
