12
Treatment
Table 11. Considerations for Treatment of Patients with Psoriatic
Arthritis and Concomitant Comorbidities
Comorbidity Non-steroidal Anti-inflammatory Drugs Glucocorticoids Hydroxychloroquine Sulfasalazine Methotrexate Leflunomide Cyclosporine
Cardiovascular
Disease
C ?
Congestive Heart
Failure
C C
Obesity
C
Metabolic
Syndrome
C C
Diabetes
C C
Ulcerative Colitis
? A OL
Crohn's Disease ? A OL
Uveitis
P
b
Osteoporosis C
Malignancy
Fatty Liver Disease C C C C
Chronic Kidney
Disease
C C ? SM
Depression
Chronic Hepatitis
B
a
C C C
Chronic Hepatitis
C
a
C C C
Human
Immunodeficiency
Virus
A = Approved for primary therapy of the comorbid condition
C = Reason for caution
OL = Off-label use for the therapy of the comorbid condition
P = Preferred therapy
SM = Requires special monitoring
? = Data insufficient but concerns have been raised
Blank box = No information available
