Treatment
Table 8. SAARDs and Biologicals
Slow-acting antirheumatic drugs (SAARDs)
Apremilast
Otezla
®
Azathioprine generic
Leflunomide
Arava
®
Methotrexate generic
Sulfasalazine generic
alidomide
alomid
®
Tofacitinib
Xeljanz
®
Tumor necrosis factor inhibitors (TNFi)
Adalimumab
Humira
®
Certolizumab
Cimzia
®
Etanercept
Enbrel
®
Golimumab
Simponi
®
Infliximab
Remicade
®
Biologicals other than tumor necrosis factor inhibitors
Abatacept
Orencia
®
Anakinra
Kineret
®
Rituximab
Rituxan
®
Tocilizumab
Actemra
®
Ustekinumab
Stelara
®
AS and:
Advanced hip arthritis
Severe kyphosis
Acute iritis
Recurrent iritis
IBD
Hip Arthroplasty
Elective spine osteotomy
Treatment by ophthalmologist
At home topical GC
Use infliximab or adalimumab over etanercept
Use TNFi monoclonals over etanercept
No preferred NSAID
Consider at specialized centers
Figure 3. Management of Stable AS
