Grading System Strength of Recommendation
Grade 1 = stronga Grade 2 = weakerb
Quality of Evidence A = high B = moderate b Grade 2 suggests that individual patient values may lead to different choices. C = low
a Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs.
Abbreviations ACCP, American College of Chest Physicians; ACS, acute coronary syndrome; ACT, activated clotting time; APTT, activated partial thromboplastin time; BBB, bundle-branch block; CAD, coronary artery disease; CI, confidence interval; d, day(s); dL, deciliter; FTT, Fibrinolytic Therapy Trialists; GP, glycoprotein; h, hour(s); HIT, heparin-induced thrombocytopenia; HR, hazard ratio; ICH, intracranial hemorrhage; IRA, infarct-related artery; IV, intravenous; kg, kilogram; LMWH, low-molecular-weight heparin; MI, myocardial infarction; min, minute(s); mg, milligram; OR, odds ratio; PCI, percutaneous coronary intervention; PE, pulmonary embolism; PO, oral; PTCA, percutaneous transluminal coronary angioplasty; RR, relative risk; RRR, relative risk reduction; s, second(s); subcut, subcutaneous; STE, ST-segment elevation; STEMI, ST-segment elevation myocardial infarction; tPA, tissue plasminogen activator; UFH, unfractionated heparin; VTE, venous thromboembolism
Source Goodman SG, Menon V, Cannon CP, Steg G, Magnus Ohman EM, Harrington RA. Acute ST-segment elevation myocardial infarction. Chest. 2008;133(6 Suppl):708S-775S. Available at: http://chestjournal.org/cgi/content/abstract/133/6_suppl/708S. Accessed: 5/9/09.
Disclaimer
This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.
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