Grading System Strength of Recommendation Grade 1 = stronga
Grade 2 = weakerb a
Quality of Evidence A = high B = moderate C = low
Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. b Grade 2 suggests that individual patient values may lead to different choices.
Abbreviations ACCP, American College of Chest Physicians; ACS, acute coronary syndrome; AF, atrial fibrillation; APTT, activated partial thromboplastin time; bid, twice a day; BMS, bare-metal stent; CAD, coronary artery disease; CHADS2
, congestive heart failure, hypertension, age
≥ 75 years, diabetes mellitus, prior stroke or transient ischemic attack; DES, drug-eluting stent; DVT, deep venous thrombosis; FDA, US Food and Drug Administration; INR, international normalized ratio; IV, intravenous; LMWH, low-molecular-weight heparin; MI, myocardial infarction; PO, by mouth; Rx, prescription; subcut, subcutaneous; STEMI, ST-segment elevation myocardial infarction; TEE, transesophageal echocardiography; UFH, unfractionated heparin; VKA, vitamin K antagonist
Source You JJ, Singer DE, Howard PA, et al. Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e531S-e575S. doi:10.1378/chest.11-2304.
Disclaimer
This Guideline attempts to define principles of practice that should produce high-quality patient care. It focuses on the needs of primary care practice, but also is applicable to providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgement concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool.
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