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Dry Eye Syndrome

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5 Î Identifying characteristics of the causative factors, such as adverse environments, prolonged visual efforts, or ameliorating circumstances, is helpful in diagnosing dry eye. (III, G, S) Î Supporting clinical observations and tests are used to confirm the diagnosis. (III, G, S) Î Questions about patient symptoms and signs, exacerbating conditions, duration of symptoms, and ocular history may elicit helpful information. (III, G, S) Î All patients should have a comprehensive adult medical eye evaluation at the recommended intervals. (II++, G, S) Î The initial evaluation of a patient who presents with symptoms suggestive of dry eye should include those features of the comprehensive adult medical eye evaluation relevant to dry eye. (II++, G, S) Î The external examination should pay particular attention to the skin, eyelids, adnexa, proptosis, cranial nerve function, and hands. (III, G, S) Î Evaluation of conjunctival staining is helpful but underutilized. (III, In, D) Î Patients with moderate punctate staining of the cornea and/or conjunctiva should be considered for testing for an underlying Sjögren syndrome, since these patients will require a multidisciplinary approach. (III, In, D) Î Lissamine green dye is NOT recommended for evaluating corneal epithelial disease. (III, In, D) Î The Schirmer test can be performed to evaluate aqueous tear production, but it is well recognized that it gives variable results and should not be used as the sole criterion for diagnosing dry eye. (III, In, D) Î The slit-lamp biomicroscopy evaluation should focus on the tear film, eyelashes, anterior and posterior eyelid margins, puncta, conjunctiva, and cornea. (III, G, S) Î A detailed review of systems should be performed for any patient who has clinically significant dry eye. (III, G, S) Diagnosis

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