2
Etiology
Figure 1. Inflammatory Mediators in Dry Eye
Secretory Dysfunction
Lacrimal Gland
Meibomian Gland
Ocular Surface
Epithelial Disease
(Dry Eye)
Adhesion
Molecules
T Cell
Infiltration
Rheumatoid Arthritis
Sjögren's Syndrome
Hyperosmolar
Tears
MMPs Apoptosis
Modified from Pflugfelder SC. Antiinflammatory therapy for dry eye. Am J Ophthalmol.
2004;137:338, with permission from Elsevier.
MMPs, matrix metalloproteinases
Ocular Surface
Inflammation
Female Gender
Androgen Deficiency
Cytokines
Chemokines
