15
Pediatric Dosage
b
Comment
N/A N/A
25-50 mg/kg/day in 3 or 4 divided
doses PO
N/A
40 mg/kg/day in 3-4 divided doses PO
d
Some strains of S. aureus and S. pyogenes
may be resistant.
20 mg/kg/day in 3 divided doses PO N/A
25 mg/kg/day of the amoxicillin
component in 2 divided doses PO
N/A
Apply to lesions bid For patients with limited number of lesions.
Apply to lesions tid For patients with limited number of lesions.
100-150 mg/kg/day in 4 divided doses Parental drug of choice.
Inactive against MRSA.
50 mg/kg/day in 3 divided doses • For penicillin-allergic patients except those
with immediate hypersensitivity reactions.
• More convenient than nafcillin with less
bone marrow suppression.
25-40 mg/kg/day in 3 divided doses IV
or
25-30 mg/kg/day in 3 divided doses PO
• Bacteriostatic.
• Potential for cross-resistance and emergence
of resistance in erythromycin-resistant strains.
• Inducible resistance in MRSA.
25-50 mg/kg/day in 4 divided doses PO • Oral agent of choice for methicillin-
susceptible strains in adults.
• Not used much in pediatrics
25-50 mg/kg/day in 4 divided doses PO • For penicillin-allergic patients except those
with immediate hypersensitivity reactions.
• A primary option in pediatrics because of its
availability as a suspension.
NOT recommended for age <8 years
e
• Bacteriostatic.
• Limited recent clinical experience.
8-12 mg/kg (based on trimethoprim
component) in either 4 divided doses
IV or 2 divided doses PO
• Bactericidal.
• Efficacy poorly documented.
