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Skin and Soft Tissue Infections

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13 Cellular Immunodeficiency Î Consider immediate consultation with a dermatologist familiar with cutaneous manifestations of infection in patients with cellular immune defects (eg, those with lymphoma, lymphocytic leukemia, recipients of organ transplants, or those receiving immunosuppressive drugs such as anti-tumor necrosis factors or certain monoclonal antibodies) (WR-L). Î Consider biopsy and surgical debridement early in the management of these patients (WR-L). Î Empiric antibiotics, antifungals and/or antivirals should be considered in life-threatening situations (WR-M). The use of specific agents should be decided with the input of the primary team, dermatology, infectious disease and other consulting teams (SR-M).

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