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Active bleeding associated
with oral anticoagulant
Non-life-threatening
bleeding
• Supportive measures
• Consider hemodialysis
(dabigatran)
• Hold an anticoagulant
Life-threatening bleeding or
uncontrolled major bleeding due
to which oral anticoagulant
Dabigatran Warfarin
Idarucizumab
(1, B-NR)
Activated PCC if
idarucizumab is not
available
(2a, C-LD)
4-factor PCC and
intravenous vitamin K
(1, A)