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Management
Figure 13. Active Bleeding Associated with Oral Anticoagulant
Minor bleeding
Andexanet alfa
For apixaban or rivaroxaban
(1, B-NR)
For edoxaban
(1, C-LD)
• Supportive measures
• May hold an
anticoagulant
until hemostasis is
achieved
Factor Xa inhibitor
4-factor PCC
Oral factor Xa
inhibitors
(1, C-LD)
