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Issue link: https://eguideline.guidelinecentral.com/i/387793
27 Obesity, alcohol abuse Metabolic/ mitochondrial dysfunction Oxidative stress NLRP3 Inflammasome activation Sleep-disordered breathing Autonomic dysfunction Transcriptional and post- transcriptional remodeling Disrupted Ca 2+ cycling, ion channel remodeling Increased atrial ectopy (premature atrial contractions [PACs])
