8
Treatment
Table 2a. Commonly Used Medications
Medication
(Brand)
Recommended Dose
Range (mg/day)
a
Chlorpromazine
Equivalents
(mg/day)
b
Half-life (hours)
Conventional antipsychotic agents
Phenothiazines
Chlorpromazine
(orazine)
300-1000 100 6
Fluphenazine
(Prolixin)
6-20 2 33
Perphenazine
(Trilafon)
12-64 10 10
Trifluoperazine
(Stelazine)
15-50 5 34
Butyrophenone
Haloperidol
(Haldol,
Serenace)
6-40
(higher doses especially
when failing to respond
to doses up to 20 mg)
2 21
Others
Loxapine
(Loxitane)
30-100 10 4
iothixene
(Navane)
15-50 5 34
a
Dose range recommendations are adapted from the 2009 Schizophrenia Patient Outcome
Research Team recommendations.
b
Chlorpromazine equivalents represent the approximate dose equivalent to 100 mg of
chlorpromazine (relative potency).
