Diagnosis
3
Diagnosis of Hypogonadism in Men
Diagnosis of Men with Suspected Hypogonadism
➤ Endocrine Society (ES) recommends diagnosing hypogonadism in men
with symptoms and signs of testosterone deficiency and unequivocally
and consistently low serum total testosterone (TT) and/or free
testosterone (FT) concentrations (when indicated). (1|⊕⊕⊕
)
Screening and Case Detection for Hypogonadism
➤ ES recommends against routine screening of men in the general
population for hypogonadism. (1|⊕⊕
)
Distinguishing Between Primary or Secondary Hypogonadism
➤ In men who have hypogonadism, ES recommends distinguishing
between primary (testicular) and secondary (pituitary-hypothalamic)
hypogonadism by measuring serum luteinizing hormone and follicle-
stimulating hormone concentrations. (1|⊕⊕⊕
)
Evaluation for Determining the Etiology of Hypogonadism
➤ In men with hypogonadism, ES suggests further evaluation to identify
the etiology of hypothalamic, pituitary, and/or testicular dysfunction.
(2|⊕⊕
)
