106 Commerce Street, Suite 105
Lake Mary, FL 32746
TEL: 407.878.7606 • FAX: 407.878.7611
Order additional copies at GuidelineCentral.com
Copyright © 2018 All rights reserved
ESTES1863
Disclaimer
is pocket guide attempts to define principles of practice that should produce high-quality
patient care. It focuses on the needs of primary care practice, but also is applicable to providers
at all levels. is pocket guide should not be considered exclusive of other methods of care
reasonably directed at obtaining the same results. e ultimate judgment concerning the
propriety of any course of conduct must be made by the clinician aer consideration of each
individual patient situation. Neither IGC, the medical associations, nor the authors endorse
any product or service associated with the distributor of this clinical reference tool.
Source
Bhasin S et al. Testosterone erapy in Men With Hypogonadism: An Endocrine Society
Clinical Practice Guideline. J Clin Endocrinol Metab., May 2018, 103(5):1–30.
Abbreviations
AAS, androgenic-anabolic steroid; ACTH, adrenocorticotropic hormone; AUA,
America Urological Association; BMD, bone mineral density; CDC, Centers for Disease
Control and Prevention; CT, computed tomography; DHT, dihydrotestosterone; DRE,
digital rectal examination; E2, estradiol; ES, Endocrine Society; FDA, US Food and
Drug Administration; FSH, follicle stimulating hormone; FT, free testosterone; IM,
intramuscular; IPSS, International Prostate Symptom Score; KS, Klinefelter syndrome;
LH, luteinizing hormone; LUTS, lower urinary tract symptoms; PSA, prostate-specific
antigen; SC, subcutaneous; SHBG, sex hormone-binding globulin; SMD, standardized
mean difference; T, testosterone; TT, total testosterone
Grading System
Strength of
Recommendation
1 = strong 2 = conditional UGPS = ungraded
good practice statement
Quality of
Evidence
⊕⊕⊕⊕
= high
⊕⊕⊕
= moderate
⊕⊕
= low
⊕
= very low
