15
Table 7. Potential Adverse Effects of T Replacement
Buccal T tablets
• Alterations in taste
• Irritation of gums
Pellet implants
• Infection, expulsion of pellet
T nasal gel
• Rhinorrhea, epistaxis, nasal discomfort, nasal congestion, parosmia
Oral tablets (methylT)—not recommended
• Effects on liver and cholesterol
b
a
e mechanism of cough, which has been reported rarely aer intramuscular
injections of T undecanoate and even more rarely aer T enanthate and cypionate, is
unknown, but it has been attributed to pulmonary oil microembolization.
b
Liver toxicity has been reported mostly with oral 17α-alkylated androgens.
Adapted with permission from Bhasin et al. J Clin Endocrinol Metab. 2010;95(6):
2536–2559.
(cont'd)
