Treatment
12
Table 6. Testosterone Formulations Available Outside the
United States, but Not Approved by the FDA
Formulation Typical Starting Doses Pharmacokinetic Profile
Oral T
undecanoate
40–80 mg oral, two or three
times daily with meals
When administered in
castor oil, T undecanoate
is absorbed through the
lymphatics, bypassing the
portal system; considerable
variability in the same
individual on different days
and among individuals
T-in-adhesive
matrix patch
Two 60 cm
2
patches
delivering ~4.8 mg
Restores serum T, DHT,
and E2 to the physiological
range