Disclaimer
is Guideline attempts to define principles of practice that should produce high-quality patient
care. It is applicable to specialists, primary care practitioners, and providers at all levels. is
Guideline should not be considered exclusive of other methods of care reasonably directed at
obtaining the same results. e ultimate judgment concerning the propriety of any course of
conduct must be made by the clinician aer consideration of each individual patient situation.
Neither IGC, the medical associations, nor the authors endorse any product or service associated
with the distributor of this clinical reference tool.
Abbreviations
ABI, ankle-brachial index; ACC, American College of Cardiolog y; AHA, American
Heart Association; ALT, alanine transaminase; ASCVD, atherosclerotic cardiovascular
disease; AST, aspartate aminotransferase; BAS, bile acid sequestrants; bid, twice daily;
CAC, coronary artery calcium; CK, creatine kinase; COR, Class of Recommendation;
CTT, Cholesterol Treatment Trialists Collaboration eGFR, estimated glomerular
filtration rate; FDA, Food and Drug Administration; HDL-C, high-density lipoprotein
cholesterol; HF, heart failure; IDEAL, Incremental Decrease through Aggressive Lipid
Lowering study; LDL-C, low-density lipoprotein cholesterol; LOE, Level of Evidence;
MI, myocardial infarction; NHLBI, National Heart, Lung, and Blood Institute; NYHA,
New York Heart Association; RCTs, randomized controlled trials; TIA, transient
ischemic attack; ULN, upper limit of normal
Source
Stone NJ, Robinson JG, Lichtenstein AH, Bairey Merz CN, Blum CB, Eckel RH,
Goldberg AC, Gordon D, Levy D, Lloyd-Jones DM, McBride P, Schwartz JS, Shero ST,
Smith SC Jr, Watson K, Wilson PWF. 2013 ACC/AHA guideline on the treatment of
blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the
American College of Cardiolog y/American Heart Association Task Force on Practice
Guidelines. Published online before print November 12, 2013, J Am Coll Cardiol: doi:
10.1016/j.jacc.2013.11.002 and Circulation: doi: 10.1161/01.cir.0000437738.63853.7a.
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