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Management
Table 10E. Management of Hematologic/Oncologic Disease
Manifestation Associated IEI
Severe anemia or thrombocytopenia SCID, CID
Autoimmune anemia or
thrombocytopenia
Antibody deficiencies, immunodysregulatory
disorders
Autoimmune neutropenia Antibody deficiencies, immunodysregulatory
disorders
Lymphoproliferative disorders CID with EBV susceptibility or risk of EBV-
driven malignancies
Malignancies All IEI
Hemophagocytic lymphohistiocytosis
(HLH)/ macrophage activation
syndrome (MAS)
All IEI
