Hyperthyroidism
38
Examples
Hydronephrosis Preauricular sinus and/or cyst
Propylthiouracil
b
Face and neck
Urinary system
Respiratory system
Circulatory system
Digestive system
Integumentary system
Odds ratio 0.1 0.2 0.4 1 2 4 8 12 20
First Trimester ATD Exposure and Congenital Malformation Risks
Figure 6. Risks of Antithyroid Drugs During Pregnancy
Prevalence of congenital malformations
Unexposed ATD group PTU use only
5.9%
(N=170,716/2,872,109)
Within 1 year of birth
a
7.0%
(N=699/9,930)
5.7%
(N=45,982/811,730)
Within 2 years of birth
b
8.0%
(N=45/564)
a
Seo GH, et al. Ann Intern Med 2018;168(6):405–413
b
Andersen SL, et al. J Clin Endocrinol Metab 2019;104(2):6040–6048
