9
LDL-C <70 mg/dL (1.8 mmol/L)
Non–HDL-C <100 mg/dL
(2.6 mmol/L)
LDL-C <55 mg/dL (1.4 mmol/L)
Non–HDL-C <85 mg/dL
(2.2 mmol/L)
PREVENT-ASCVD ≥10%
• If TG ≥150 mg/dL to 499 mg/dL,
apoB goal: <70 mg/dL
N/A
With FH, ASCVD risk factors, or
subclinical atherosclerosis
Severe hypercholesterolemia
or HeFH with clinical ASCVD
With ASCVD risk factors or
diabetes-specific risk factors
• apoB goal: <70 mg/dL
N/A
• CAC ≥100 to 299 AU or ≥75th
percentile for age, sex, race
• CAC ≥300 to 999 AU
°
Optional goal: LDL-C <55 mg/dL,
non–HDL-C <85 mg/dL and
consider apoB goal <55 mg/dL
CAC ≥1000 AU
• With clinical ASCVD not at very
high risk
°
apoB goal: <70 mg/dL
• Age 40–75 y with ≥1 ASCVD
risk factor
°
apoB goal: <70 mg/dL
With clinical ASCVD at very
high risk
• apoB goal: <55 mg/dL
Not at very high risk
• Optional goal: LDL-C <55 mg/dL,
non–HDL-C <85 mg/dL and
consider apoB goal <55 mg/dL
• At very high risk
°
apoB goal: <55 mg/dL
• With CKD
