58
Management
(cont'd)
Figure 10. Clinical ASCVD: Criteria for Defining "At Very High
Risk" in Adults
Major ASCVD Events
• ACS within past 12 mo
• History of MI (other than ACS above)
• History of ischemic stroke
• Symptomatic PAD
High-Risk Conditions
• Age ≥65 y
• Coronary bypass or percutaneous intervention
• Current smoker
• Diabetes
• Hx of congestive heart failure
• Hypertension
• LDL-C ≥100 mg/dL (2.6 mmol/L) despite
maximally tolerated statin + ezetimibe
ACS indicates acute coronary syndrome; ASCVD, atherosclerotic cardiovascular disease;
Hx, history; LDL-C, low-density lipoprotein-cholesterol; MI, myocardial infarction; and PAD,
peripheral artery disease.
Adapted with permission from Grundy et al. Copyright © 2018 American Heart Association, Inc.
and American College of Cardiology Foundation.
