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AHA/ASA Early Management of Acute Ischemic Stroke 2026

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49 5.1. Stroke Units COR LOE Recommendation 1 B-R 1. In patients with AIS of all ages, treatment within an organized inpatient stroke care unit supported by a specialty trained, interdisciplinary care team (ie, acute stroke units, rehabilitation stroke units, comprehensive stroke units, and mixed rehabilitation units) that incorporates standardized stroke care order sets and protocols is recommended to reduce the odds of poor outcomes and death. Figure 5. Characteristics of an Organized Specialized Inpatient Care Unit: Flow Diagram • Assessment of stroke diagnosis/mechanism by specialized stroke provider • Assessment and monitoring by nurses with continuous specialized training in stroke • Stroke mechanism treatment plan • Early goal setting and onset of rehabilitation by physical, occupational, and speech therapy • Integration with specialized rehabilitation nursing care and caregivers • Collaborative planning with interdisciplinary clinical team • Early assessment of discharge needs • Integration of patient and caregivers with a focus on continued educational support • Coordination of follow-up care • Standardized acute stroke care order sets utilization • Physical and medical complications management guided by clinical practice guidelines/protocols • Early rehabilitation assessment and mobilization by the stroke team • Multidisciplinary team care to include nursing and caregivers with weekly meetings Assessment and Monitoring Rehabilitation Discharge Planning Clinical Management (First 5 days) In-Hospital Management of AIS: General Supportive Care

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