47
ABCD2 indicates Age, Blood
Pressure, Clinical Features, Duration,
and Diabetes (TIA risk score); AIS,
acute ischemic stroke; Asa, aspirin;
Athero, atherosclerosis; CHANCE,
Clopidogrel in High-risk patients with
Acute Nondisabling Cerebrovascular
Events; CHANCE 2, Clopidogrel versus
Ticagrelor in High-risk Patients with
Acute Nondisabling Cerebrovascular
Events; DAPT, Dual Antiplatelet erapy;
INSPIRES, Innovative Stroke Prevention
and Intervention Research Study; LKN,
last known normal; MT, mechanical
thrombectomy; NIHSS, National
Institutes of Health Stroke Scale; POINT,
Platelet-Oriented Inhibition in New
TIA and Minor Ischemic Stroke; SAPT,
Single Antiplatelet erapy; THALES,
Acute Stroke or Transient Ischemic Attack
Treated with Ticagrelor and ASA for
Prevention of Stroke and Death; and TIA,
transient ischemic attack.
YES
DAPT
DAPT
SAPT
SAPT
SAPT
Thrombolysis
and MT section
2a
Clopidogrel + Asa
×
21 days
YES
YES
NO
NO
1
Athero (>50%)
1
LKN 24–72 hr
+ NIHSS ≤5
or ABCD ≥4
INSPIRES
INSPIRES
(patients with
presumed
athero)
THALES
2b
Ticagrelor + Asa
×
30 days
2a
Clopidogrel + Asa
×
21 days
OR
